Metabolic Syndrome: Prevalence of Its Components in Post Menopausal Females

Abstract

Introduction: Metabolic syndrome is a cluster of metabolic abnormalities characterized by abdominal

obesity, hyperglycemia, decreased high density lipoprotein (HDL), increased Triglycerides and high blood

pressure, which predispose the individual at higher risk for both cardiovascular disease (CVD) and type 2

diabetes. Postmenopausal state is considered as a vulnerable period for developing MS.

Aims and Objectives: To study the Prevalence of metabolic syndrome and its components in postmenopausal

women.

Material and Method: This study was conducted in the Department of biochemistry, MMIMSR, MMDU,

Mullana, Ambala. A total of 100 postmenopausal women in the age group of above 45 years were recruited

for this study after assessing their eligibility according to the selection criteria.

Biochemical Investigations: Estimation of Fasting Serum glucose was done on Erba chem 7 analyzer

and Total cholesterol, HDL and Serum Triglycerides was done on Dimension® clinical chemistry system

manufactured by Siemens Healthcare Diagnostics (US).

Results: The mean triglycerides and fasting serum glucose levels were significantly high (<0.001) among

postmenopausal women with metabolic syndrome. Overall prevalence of metabolic syndrome was 29%.

Conclusions: Evaluating the biochemical parameters in postmenopausal women is useful for assessing the

risk of developing metabolic syndrome in them. Monitoring the health status of these females can help to

reduce the Prevalence of metabolic syndrome and thus the risk of developing cardiovascular disease.