The Relationship between Burden Symptoms and Uncertainty in Illness in Cancer Patients in Aceh
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Abstract
Objective: Uncertainty in illness is a condition in which individuals have difficulty predicting, controlling, and understanding the development of their disease. In cancer patients, the high severity of symptoms has the potential to increase uncertainty in illness. This study aims to explore the relationship between burden symptoms and uncertainty in illness in cancer patients at one of the referral hospitals in the province of Aceh, Indonesia.
Material and Methods: This study is a quantitative research with a correlational analytical design with a cross-sectional approach and was carried out from January to February 2025 at one of the referral hospitals in Aceh province. From a total population of 220 patients, 142 samples were selected through purposive sampling techniques. The sample consisted of patients with breast cancer, ovarian cancer, and cervical cancer. Data were collected using questionnaires consisting of sociodemographic characteristics, MD Anderson Symptom Inventory (MDASI), and Mishel Uncertainty in Illness Scale (MUIS). Data analysis was carried out using chi-square.
Results: The results showed that the majority of respondents (n=142) were patients with breast, ovarian, and cervical cancer. A total of 112 patients (78.9%) experienced a high level of uncertainty in illness, while 30 respondents (21.1%) experienced a low level of uncertainty in illness. Then out of a total of 142 respondents, 77 respondents (54.2%) experienced burden symptom, while 65 respondents (45.8%) experienced mild and moderate burden symptom. This shows that there is a significant relationship between burden symptom and uncertainty in illness (p = 0.030).
Conclusion: There was a significant relationship between symptom severity and uncertainty in illness (p = 0.030).
Recommendation: It is recommended that further research be conducted with longitudinal or mixed methods design to gain a deeper understanding of the dynamics of uncertainty in illness.
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References
WHO. Cancer. World Health Organization. 2023. p. 1–8.
Globocan. Globocan 2022: Data kanker global terbaru menunjukkan peningkatan insiden dan kesenjangan yang mencolok [Internet]. UICC. 2024 [cited 2024 Jul 10]. p. 1–9. Available from: https://www.uicc.org/news/globocan-2022-latest-global-cancer-data-shows-rising-incidence-and-stark-inequities
World Cancer Research Internasional. Data kanker di seluruh dunia [Internet]. World Cancer Research Internasional. 2022 [cited 2024 Sep 12]. p. 5. Available from: https://www.wcrf.org/cancer-trends/worldwide-cancer-data/
Ferlay J, M. Lam F E, Laversanne M, Colombet M ML, Piñeros M ZA, Soerjomataram I, et al. Global Cancer Observatory: Cancer Today [Internet]. International Agency for Research on Cancer. 2024. p. 1–2. Available from: https://gco.iarc.who.int/today
kemenkes. Support system; teman dalam segala situasi. In: Direktorat Jenderal Pelayanan Kesehatan [Internet]. 2022. p. 1–5. Available from: https://yankes.kemkes.go.id/view _artikel/613/support-system-teman-dalam-segala-situasi
Dwi A. Jumlah Penyintas Kanker di Aceh Capai 1.318 Orang. In: Republik Merdeka Kantor Berita Politik RMOLID. 2024. p. 1–4.
Cleeland CS, Zhao F, Chang VT, Sloan JA, O’Mara AM, Gilman PB, et al. The symptom burden of cancer: Evidence for a core set of cancer‐related and treatment‐related symptoms from the Eastern Cooperative Oncology Group Symptom Outcomes and Practice Patterns study. Cancer [Internet]. 2013 Dec 15;119(24):4333–40. Available from: https://acsjournals.onlinelibrary.wiley.com/doi/10.1002/cncr.28376
Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin [Internet]. 2020 Jan 8;70(1):7–30. Available from: https://acsjournals.onlinelibrary.wiley.com/doi/10.3322/caac.21590
Alligood RM. Nursing Theorists And Their Work Eighth Edition. In: Alligood, R M, editor. Nursing Theorists And Their Work Eighth Edition. 8th ed. United States of America: ELSEVIER MOSBY; 2014. p. 1–765.
Gonzalez G, Durantez VV, Martin-Abreu C, Cruz-Castellanos P, Hernandez R, Gil-Raga M, et al. Fatigue, Emotional Distress, and Illness Uncertainty in Patients with Metastatic Cancer: Results from the Prospective NEOETIC_SEOM Study. Curr Oncol [Internet]. 2022 Dec 8;29(12):9722–32. Available from: https://www.mdpi.com/1718-7729/29/12/763
Guan T. PATIENTS, CAREGIVERS, AND ILLNESS UNCERTAINTY: INFLUENCES ON COPING AND QUALITY OF LIFE. 2019;1–23.
Guan T, Qan"irYousef, Song L. Tinjauan sistematis terhadap intervensi manajemen ketidakpastian penyakit untuk pasien kanker dan perawat keluarga mereka. Exp Hematol Oncol [Internet]. 2021;4623–40. Available from: https://link.springer.com/article/10.1007/s00520-020-05931-x
Reilly CM, Bruner, Deborah Watkins Mitchell SA, Minasian. LM, Basch E, Dueck AC, Cella D, et al. A Literature Synthesis of Symptom Prevalence and Severity in Persons Receiving Active Cancer Treatment. Support Care Cancer [Internet]. 2015;21(6):1525–50. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC4299699/
Fardell JE, Yee S, Tan C, Kerin-ayres K, Dhillon HM, Vardy JL. Symptom Clusters in Survivorship and Their Impact on Ability to Work among Cancer Survivors. Cancers (Basel) [Internet]. 2023;15(21):1–11. Available from: https://www.mdpi.com/2072-6694/15/21/5119
Büthe L, Westhofen G, Hille A, Büntzel J. Symptom Burden and Dietary Changes Among Older Adults with Cancer : A Cross-Sectional Study. Curr Oncol [Internet]. 2024;31(12):7663–85. Available from: https://www.mdpi.com/1718-7729/31/12/565
Wei J, Bai Z, Bu M, Dang G, Wu X, Zhou J. Influence of symptom burden on social alienation in lung cancer patients receiving chemotherapy : the chain mediating effect of perceived social support and positive psychological capital. BMC Psychol [Internet]. 2025;13:1–10. Available from: https://bmcpsychology.biomedcentral.com/articles/10.1186/s40359-025-02403-x
Tai SY, Lee CY, Wu CY, Hsieh HY, Huang JJ, Huang CT, et al. Symptom severity of patients with advanced cancer in palliative care unit: Longitudinal assessments of symptoms improvement. BMC Palliat Care [Internet]. 2016;15(1):1–7. Available from: http://dx.doi.org/10.1186/s12904-016-0105-8
Lan CF, Nie CL, Lin YJ. Uncertainty in illness and the coping styles of severe patients with COVID-19: current status and correlation. Epidemiol Infect [Internet]. 2021 Jul 8;149:e174. Available from: https://www.cambridge.org/core/product/identifier/S0950268821001448/type/journal_article
Hall DL, Mishel MH, Germino BB. Living with cancer-related uncertainty: associations with fatigue, insomnia, and affect in younger breast cancer survivors. Support Care Cancer [Internet]. 2014 Sep 12;22(9):2489–95. Available from: file:///C:/Users/Carla%0ACarolina/Desktop/Artigos%0Apara%0Aacrescentar%0Ana%0Aqualificação/The%0Aimpact%0Aof%0Abirth%0Aweight%0Aon%0Acardiovascular%0Adisease%0Arisk%0Ain
Safar H. Hubungan Antara Beban Gejala, Ketidakpastian Penyakit, Dukungan Sosial yang Dirasakan, dan Kualitas Hidup Terkait Kesehatan pada Wanita Kuwait Penderita Kanker Payudara [Internet]. Case Western Reserve University; 2021. Available from: https://www.proquest.com/openview/3bdcb1617f79f7a09e29cbfa25a4fa83/1?pq-origsite=gscholar&cbl=18750&diss=y