Systematic Review on the Efficacy of Icon Resin Infiltration on White Spot Lesions

Abstract

Background: Resin infiltration is a new therapeutic technique for WSLs (white spot lesions) that may bridge
nonoperative and operative treatment options. It’s a minimally invasive procedure for filling, reinforcing,
and stabilizing demineralized enamel without drilling or compromising good tooth structure. It has also
been found to slow the progression of caries in lesions that are too advanced to be treated with fluoride. The
current investigation of this systematic review is to evaluate the efficacy of ICON® resin infiltration on WSLs.
This literature review was conducted and reported according to the PRISMA (Preferred Reporting Items for
Systematic Review and Metaanalysis) statement. Seven databases (PubMed, Cochrane Library, CINAHL, OVID
MEDLINE, EMBASE, Grey Literature, Wiley Online Library) were used. The MeSH terms used were ‘Icon resin
infiltration, ‘ white spot lesions, and ‘clinical trials. PICOS analysis of Population- Participants with white spot
lesions; Intervention- Icon Resin Infiltration; Comparison- Comparing with other different therapies; Outcome-
Regression or disappearance of lesions; Study design- Randomized controlled trials. Five cross-sectional studies
were included in this systematic review for the quality assessment of the efficacy of Icon resin infiltration on
white spot lesions. All five studies reported a statistically significant difference between the Icon resin infiltration,
lesion loss ratio, and color change. This systematic review concludes that the Icon resin infiltration on white spot
lesion is effective during the initial period, i.e. first three months. Over time there is a color change in its masking.
However, it is effective in reducing the lesion loss ratio.