Estimation of HsCRP and Cardiac Troponin I in Ischemic Heart Disease Iraqi Patients

Abstract

The present study is an attempt to investigate the changes in serum cardiac troponin (cTn) and Highsensitivity
C-reactive protein (HsCRP) markers levels in Iraqi ischemic heart disease (IHD) patients
including stable angina (SA), unstable angina (UA) and myocardial infarction (MI) compared to the healthy
controls (HC), and to evaluate the importance of the HsCRP between these diseases combination groups
from the dignostic point of view, in addition to find a significant correlation between HsCRP level and some
IHD risk factors. The IHD’s mortality surpass that of every major disease, so it is important that to get
such research especially among Iraqi patients. IHD is defined as blood flow reduction to the heart muscle
due to build-up of fatty strips (plaque) in the coronary arteries, it exists when the coronary blood flow
becomes incapable of both delivering sufficient oxygen (O2) to the myocardium and taking away the carbon
dioxide (CO2) from the cells. Collecting the blood samples from one hundred thirty IHD patients (during the
period from October 2020 to February 2021) with ages ranged (30-80) years, of both genders, investigated
for HsCRP by enzyme linked immune sorbent assay (ELISA) technique and cardiac Troponin (cTn I) by
immunochromography method. This study observed that the HsCRP marker is a reliable diagnostic indicator
in both MI and UA groups (but not in SA patients), and in all diseases combination groups, and that there
was significant correlations between each of the triglyceride level and the hypertension, and the HsCRP
marker level, only in the MI group, but not in SA and UA patients.