Drug Interaction of Hypericum Perforatum with Routine Chemical Drugs

Abstract

In traditional medicine, Hypericum perforatum L. is used as an antidepressant, diuretic, analgesic, antiseptic
and wound healing, anticonvulsant, rheumatism and chronic gastrointestinal spasms, abortion, sciatica, and
for the treatment of infectious diseases such as syphilis, tuberculosis, dysentery, pertussis, worm excretion,
and malaria. H. perforatum interferes with cardiac drugs, anesthetics, narcotics and analgesics, antibiotics,
hormonal compounds, antiviral compounds, anticonvulsants and antidepressants, organ transplantation
compounds, and iron compounds. Despite the medicinal effects of the valuable plant H. perforatum, the
single use of this plant is very effective and valuable in the treatment of diseases and disorders, but its use
with other chemical drugs due to the occurrence of drug interactions requires caution in consumption.