Immune Dysregulation in Childhood Leprosy

Authors

  • Flora Ramona Sigit Prakoeswa
  • Budi Prasetyo
  • Santi Martini
  • Hardyanto Soebono
  • Muhammad Yulianto Listiawan
  • Anang Endaryanto
  • Cita Rosita Sigit Prakoeswa

DOI:

https://doi.org/10.37506/ijfmt.v15i2.14725

Keywords:

Immune dysregulation, Childhood leprosy

Abstract

Leprosy is a chronic infection which is caused by Mycobacterium leprae. Leprosy has long been considered
a complex disease, in which host and environmental characteristics are as important as the pathogen to
determine disease outcome. Leprosy is an excellent model for examining the immunoregulatory functions.
Children are believed to be the most vulnerable group to leprosy infection due to their immature immunity.
This review is aimed to summarize the findings of previous studies about immune dysregulation in childhood
leprosy. This study highlighted the plausible maternal-fetal connection which are related in immune
dysregulation in childhood leprosy.

Author Biographies

  • Flora Ramona Sigit Prakoeswa

    Doctoral Program, Faculty of Medicine, Airlangga University, Indonesia, Department of Dermatology and
    Venereology, Faculty of Medicine, Universitas Muhammadiyah Surakarta, Indonesia

  • Budi Prasetyo

    Associate Professor,
    Department of Obstetrics and Gynecology, Faculty of Medicine, Airlangga University / Dr. Soetomo General
    Academic Hospital, Surabaya, Indonesia

  • Santi Martini

    Associate Professor, Faculty of Public Health, Airlangga University,
    Indonesia

  • Hardyanto Soebono

    Professor, Department of Dermatology and Venereology, Faculty of Medicine, Public Health and
    Nursing, Gadjah Mada University, Indonesia

  • Muhammad Yulianto Listiawan

    Associate Professor, Department of Dermatology and Venereology,
    Faculty of Medicine, Airlangga University / Dr. Soetomo General Academic Hospital, Surabaya, Indonesia

  • Anang Endaryanto

    Associate Professor, Department of Pediatrics, Faculty of Medicine, Airlangga University / Dr. Soetomo General
    Academic Hospital, Surabaya, Indonesia

  • Cita Rosita Sigit Prakoeswa

    Professor, Department of Dermatology and Venereology, Faculty of
    Medicine, Airlangga University / Dr. Soetomo General Academic Hospital, Surabaya, Indonesia

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Published

2021-03-24

Issue

Vol. 15 No. 2 (2021): Indian Journal of Forensic Medicine & Toxicology

Section

Articles

License

https://creativecommons.org/licenses/by-nc/2.0/deed.en

How to Cite

Immune Dysregulation in Childhood Leprosy . (2021). Indian Journal of Forensic Medicine & Toxicology, 15(2), 2356-2364. https://doi.org/10.37506/ijfmt.v15i2.14725