Molecular Physical Properties of Cryogloblin in Patients with Hepatitis B Virus in Al-Najaf Province

Abstract

Cryoglobulins (CGs) are a cold precipitating abnormal immunoglobulins. The incidence of hepatitis B was

discovered to be greater in age groups (46-55 years) relative to othe age groups. CGs were detected in

50 (33.3%) out of 150 patients with Hepatitis B. Three types of CGs precipitation nature were identified.

Gelatinous (76%), flocculate (20%), and crystallineous (4%). No relation was found between patient’s age

and CGs molecular physical properties.

The cryocrit test of 50 serum samples revealed that CGs are characterized by their reversible precipitation at

4ºC between 12 hours to five days and solubility time at 37ºC ranged between half an hour and three hours.